If you are thinking whether we can improve the look and feel of the SharePoint site a perfect example is the Glu Mobile site. If you visit them at http://www.glu.com you will hardly believe that it is done by SharePoint. But the truth is it is SharePoint.
If you would like to know how they did it read the following 3 articles discussing on its design and development.
http://blogs.msdn.com/sharepoint/archive/2007/06/14/moss-has-got-game-glu-mobile-s-website-www-glu-com-how-we-did-it-part-1-of-3.aspx
http://blogs.msdn.com/sharepoint/archive/2007/06/14/moss-has-got-game-glu-mobile-s-website-www-glu-com-how-we-did-it-part-2-of-3.aspx
http://blogs.msdn.com/sharepoint/archive/2007/06/14/moss-has-got-game-glu-mobile-s-website-www-glu-com-how-we-did-it-part-3-of-3.aspx